The smart Trick of ceesdekker That Nobody is Discussing
The smart Trick of ceesdekker That Nobody is Discussing
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Spatial composition facilitates cooperation inside of a social Predicament: empirical evidence from a bacterial community
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[Laughs] ‘It had been certainly a fantastic danger! At the time, I was well knowledgeable that it could go Completely wrong Which I could develop into a lot less productive, but I just disregarded that. Curiosity has usually been my strongest driving force. And fortunately everything worked out.’
Considering the fact that 2000, Dekker has shifted the key concentration of his function toward biophysics where he reports the Attributes of single biomolecules and cells using the equipment of nanotechnology. This modification of field was driven by his fascination to the amazing performing of biological molecular structures, along with because of the extensive-term perspective that a lot of exciting discoveries is usually expected Within this discipline.[5] Recent traces of exploration in his biophysics team are during the parts of:[six]
This yielded a breakthrough. Within just only a few months, we were being capable to evaluate transport as a result of a person one-walled carbon nanotube. Depending on low-temperature experiments by a superb PhD college student in my team, Sander Tans (now a valued colleague and professor at Delft University of Technology using an Lively analysis lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes had been authentic quantum wires with very prolonged (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
All parameters had been precisely the same for every panel During this video, except for the initial placement in the 6hb rod (demonstrated in blue) to the nanopore. Simulations that terminated early as a consequence ceesdekker of translocation from the rod with the pore are marked by a grey track record.
Learning DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.
The rotors harness Strength from a nanoscale h2o and ion stream which is generated by a static chemical or electrochemical opportunity gradient while in the nanopore, which can be established via a salt gradient or utilized voltage, respectively. These synthetic nanoengines self-Arrange and operate autonomously in physiological ailments, suggesting strategies to constructing Electricity-transducing motors at nanoscale interfaces.
It had been for the duration of this era that Dekker carried out analysis on magnetic spin programs and on sound in superconductors and semiconductors.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
2006, first demonstration of molecular sorting within a lab over a chip using biomotors; discovery of nanobubbles in sound-point out nanopores; and first estimate of electrokinetic Vitality conversion in a very nanofluidic channel
Permit’s initially glimpse again for the time being once you chose to change your concentration from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.
2004, discovery of latest physics in translocation of DNA through nanopores; initially experimental examine of ions conduction in nanofluidic channels; initial electrochemistry with unique solitary-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; initially electrical docking of microtubules on kinesin-coated nanostructures; very first biophysics characterization of the mechanical Houses of double-stranded RNA; and very first one-molecule review of DNA translocation by a restriction-modification enzyme.